Weed Withdrawal Woes: Over 50% of Medical Cannabis Users for Pain Experience Symptoms

Current perceptions of cannabis have shifted dramatically, with many now viewing it as relatively harmless compared to other drugs. However, a recent study published on January 5 reveals that cannabis is not without its drawbacks. Researchers discovered that 59% of medical cannabis users for chronic pain reported experiencing moderate to severe withdrawal symptoms upon cessation.

As cannabis legalization continues to expand across the U.S.—with 15 states allowing recreational use—more individuals, particularly older adults, are incorporating cannabis into their lifestyles. While many users tout the therapeutic benefits of cannabis, it is crucial to recognize the potential risks associated with its use.

Cannabis withdrawal symptoms can manifest in both physical and psychological ways. When used frequently, the brain becomes dependent on the high levels of cannabinoids found in cannabis products. When consumption is halted, users may experience a decline in cannabinoid levels, leading to a spectrum of withdrawal symptoms. These symptoms may include irritability, depressed mood, decreased appetite, sleep disturbances, cravings, anxiety, and more.

Fortunately, cannabis withdrawal symptoms generally resolve within one to two weeks after cessation as the body readjusts its natural cannabinoid production. Unlike withdrawals from substances like alcohol, cannabis withdrawal is not life-threatening. Nonetheless, it can be uncomfortable, prompting some users to continue consumption to avoid these symptoms.

To assess the prevalence of withdrawal symptoms, researchers conducted a two-year study involving 527 medical cannabis users. The findings indicated that a significant percentage experienced withdrawal symptoms, with sleep difficulties, irritability, and anxiety being the most frequently reported issues. Furthermore, younger users, those with mental health concerns, and individuals with a longer history of use tended to experience more severe symptoms.

Our research also monitored changes in withdrawal symptom severity over time. Most participants exhibited consistent symptom severity when they ceased cannabis use, but about 10% of younger users reported worsening symptoms. As with other substances that can lead to dependency, reducing consumption frequency or amounts may mitigate these withdrawal effects.

While this study focuses solely on medical cannabis use for pain management, other research indicates that 47% of frequent cannabis users, both recreational and medical, experience withdrawal symptoms. Cannabis may not embody the tragic narrative portrayed in “Reefer Madness,” yet it is not without its complications. As cannabis use gains prevalence in the U.S., understanding the potential for withdrawal and recognizing associated symptoms becomes increasingly important.